Place of Origin: | China |
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Brand Name: | memantine hcl |
Certification: | ISO |
Model Number: | namenda generic |
Minimum Order Quantity: | 1kg |
Price: | Inquiry |
Packaging Details: | 1kg/bag,25kg/drum |
Delivery Time: | 3 work days |
Payment Terms: | T/T, Western Union, MoneyGram |
Supply Ability: | 1000kg per month |
CAS No.: | 4100-52-1 | Produce Name: | Namenda Xr |
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EINECS No.: | 255-219-6 | Coulour: | White |
Certificate: | ISO | Storage: | Store In Original Container In A Cool Dark Place. |
High Light: | pharmaceutical industry raw materials,pure paracetamol powder |
Raw material memantine hcl namenda xr generic 10mg 41100-52-1
Memantine hcl Introduction
Memantine hcl Application
Used in field of medicines,to make Memantine Hydrochloride Tablet,which treat dementia of the alzheimer type etc.
Memantine HCl is the HCl form of Memantine. Memantine is a well- known neuroprotective drug used for the treatment of Alzheimer’s disease. It is believed to be the first neuroprotective drug that has achieve clinical approval by US FDA as well as European. The development of Alzheimer’s disease involves the misfolded mutant proteins such as β-amyloid peptide (Aβ, particularly Aβ1−42). These misfolded mutant protein can increase the NMDA response and further cause severe excitotoxicity. Memantine suppresses this process through acting as the antagonist of the N-methyl-d- aspartate-sensitive glutamate receptor (NMDARs). Memantine is also under investigation as a potential treatment for other kind of neurodegenerative disorders such as HIV-associated dementia, neuropathic pain, glaucoma, depression, Huntington’s disease, ALS and movement disorders, among other.
Memantine hcl Specification
Items | Specifications | Results |
Appearance | White or almost white crystalline powder | Conforms |
Identification | IR: Shuld be consistent with the reference spectrum | Conforms |
Residue on ignition | ≤0.1% | 0.04% |
Loss on drying | ≤0.5% | 0.12% |
Heavy metals | ≤20ppm | 6ppm |
Water | ≤1.0% | 2.45% |
Individual impurity | ≤0.5% | 0.24% |
Total impurity | ≤1.0% | 1.72% |
Total chlorides | 16.2%~16.7% | 16.3% |
Assay | ≥99% by HPLC | 99.5% |